Interaction checker → St. John's Wort + Antiretrovirals

Serious — worth a conversation

Can you take St. John's Wort with antiretrovirals?

Loss of viral suppression

What happens

CYP3A4 induction sharply lowers protease inhibitor levels.

Drugs in this class include Protease inhibitors, NNRTIs.

What to do about it

Among the most serious interactions in this rule set. Worth clearing with your HIV clinician before taking it.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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Stackwise checks every pair in what you take, against your medication list, and moves things in your schedule when two of them need spacing apart.

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