Interaction checker → St. John's Wort + SSRIs / SNRIs
Serious — worth a conversationCan you take St. John's Wort with ssris / snris?
Serotonin syndrome risk
What happens
St. John's Wort inhibits serotonin reuptake on top of an SSRI or SNRI.
Drugs in this class include Sertraline, Fluoxetine, Escitalopram, Venlafaxine, Duloxetine.
What to do about it
One of the best-documented supplement–drug interactions there is. Worth raising with your prescriber before taking both.
This is general information compiled from published pharmacology, not
advice about your situation. Your dose, your other medication and your bloodwork all matter,
and a pharmacist can see those in a way this page cannot.
Check your whole stack at once
Stackwise checks every pair in what you take, against your medication list, and moves things in your schedule when two of them need spacing apart.
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