Interaction checker → St. John's Wort + Hormonal contraception

Serious — worth a conversation

Can you take St. John's Wort with hormonal contraception?

Contraceptive failure risk

What happens

CYP3A4 induction lowers hormone levels. Breakthrough bleeding and unplanned pregnancy are documented outcomes.

Drugs in this class include Combined pill, Patch, Ring, Hormonal IUD.

What to do about it

Breakthrough bleeding and unplanned pregnancy are documented outcomes. Worth a conversation with your prescriber, and a backup method in the meantime.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

Check your whole stack at once

Stackwise checks every pair in what you take, against your medication list, and moves things in your schedule when two of them need spacing apart.

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