Interaction checker → Yohimbine + SSRIs / SNRIs

Worth knowing about

Can you take Yohimbine with ssris / snris?

Yohimbine can amplify anxiety on an SSRI

What happens

Yohimbine reliably provokes anxiety and panic in susceptible people, and some SSRIs slow its clearance so the dose lands harder than expected.

Drugs in this class include Sertraline, Fluoxetine, Escitalopram, Venlafaxine, Duloxetine.

What to do about it

Worth discussing with whoever prescribes your SSRI, particularly if anxiety is part of why you take it.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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