Interaction checker → Yohimbine + MAOIs

Serious — worth a conversation

Can you take Yohimbine with maois?

Yohimbine with an MAOI can spike blood pressure

What happens

Yohimbine blocks alpha-2 receptors, which raises noradrenaline. An MAOI stops that noradrenaline being cleared, and the pair has produced hypertensive crises.

Drugs in this class include Phenelzine, Tranylcypromine, Selegiline.

What to do about it

This is one of the combinations most worth raising with your prescriber before taking both.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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