Interaction checker → Vitamin B12 + Acid reducers (PPIs)

Works well together

Can you take Vitamin B12 with acid reducers (ppis)?

PPIs reduce B12 absorption

What happens

Stomach acid is needed to free B12 from food protein.

Drugs in this class include Omeprazole, Pantoprazole, Esomeprazole.

What to do about it

Supplemental B12 bypasses the problem. This pairing is helpful, not harmful.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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