Interaction checker → Berberine + Metformin

Worth knowing about

Can you take Berberine with metformin?

Additive glucose lowering

What happens

Berberine and metformin share the AMPK mechanism; berberine also raises metformin exposure.

Drugs in this class include Metformin / Glucophage.

What to do about it

Monitor glucose. Reduce dose only under medical guidance.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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Stackwise checks every pair in what you take, against your medication list, and moves things in your schedule when two of them need spacing apart.

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