Interaction checker → Calcium + Tetracycline / quinolone antibiotics

Serious — worth a conversation

Can you take Calcium with tetracycline / quinolone antibiotics?

Calcium inactivates the antibiotic

What happens

Calcium chelates fluoroquinolone and tetracycline antibiotics, dramatically reducing absorption and risking treatment failure.

Drugs in this class include Doxycycline, Ciprofloxacin, Levofloxacin, Minocycline.

How far apart?

Leaving at least 4 hours between them avoids most of the effect.

What to do about it

Separate by at least 4 hours for the whole course.

This is general information compiled from published pharmacology, not advice about your situation. Your dose, your other medication and your bloodwork all matter, and a pharmacist can see those in a way this page cannot.

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